Thomas Karl Byrne, M.D.

Accepting New Patients
  • Medical Director, Bariatric Surgery Program
Degree M.D.
School Royal College of Physicians and Surgeons of Ireland
  • Medical College of Virginia
  • Jervis Street Hospital, Dublin
Board Certification
  • American Board of Surgery
  • Gastrointestinal Surgery
Clinical Interests
  • Bariatric surgery
  • Weight loss and nutrition
  • Gastroesophageal reflux disease (GERD)
  • Hernia surgery
  • Inguinal hernia
  • Ventral hernia
  • Gallstones
  • Nutrition
  • Diabetes
Accepts New Patients Yes


Ashley River Tower
25 Courtenay Drive
Charleston, SC 29425
Map & Directions


Dr. T Karl Byrne led the way in weight loss surgery in South Carolina, with the first bariatric program in 1992. Long before bariatric surgery was a household term, Dr. Byrne was helping patients struggling with obesity to change their lifestyles. Fast forward 25 years, and Dr. Byrne, his partner Dr. Rana Pullatt, and the team at MUSC are still leading the way with innovative procedures — MUSC is the only South Carolina center performing biliopancreatic diversion with duodenal switch (called ‘duodenal switch’ or DS for short), robotic bariatric surgery, and one of only two centers in South Carolina with accreditation to perform surgery on adolescents by the Metabolic and Bariatric Surgery accreditation and Quality Improvement Program (MBSAQIP).

After surgical training in his native Ireland, Byrne completed a research fellowship and surgical residency at the Medical College of Virginia. Through years at MUSC and more than 5,000 bariatric surgeries, Dr. Byrne has assembled a robust team and program with the most experienced bariatric advanced practice practitioners, registered dietitians, psychologists, and experts in all areas of bariatric practice at the state-of-the art Ashley River Tower building.

In addition to the gastric bypass, sleeve gastrectomy, and duodenal switch, Dr. Byrne and Dr. Pullatt perform complex revisional surgery on patients from other programs. Surgery is only the first step in a total lifestyle transformation; the interdisciplinary team who provides first class aftercare for weight loss surgery patients is critical to our patient’s long term weight maintenance.

For more information about the weight loss surgery program visit our website