Lee R Leddy, M.D., MSCR

Accepting New Patients

Accepting New Patients

Provider Image

4.9 out of 5 (182 ratings)

Degree M.D., MSCR
School University of Florida College of Medicine; Medical University of South Carolina College of Graduate Studies
  • Emory University
  • Emory University
  • Orthopaedics
  • Cancer - Sarcoma
Clinical Interests
  • Sarcoma
  • Hip replacement
  • Orthopaedic trauma surgery
  • Bone cancer
Accepts New Patients Yes


West Ashley Medical Pavilion
2060 Sam Rittenberg Boulevard
Charleston, SC 29407
Map & Directions
MUSC Health Orthopaedics - Columbia
Medical Park 3, 222 E. Medical Lane, Suite 400
West Columbia, SC 29169
Map & Directions
MUSC Health at Beaufort Memorial Okatie Medical Pavilion
122 Okatie Center Blvd North, Suite 230
Okatie, SC 29909
Map & Directions


Dr. Lee Leddy did his undergraduate work at Emory University where he received his BS in biological science while lettering on the varsity basketball team. He then received his M.D. from the University of Florida College of Medicine in Gainesville, Florida. Dr. Leddy went back to Emory University to complete his internship and residency in the Department of Orthopaedic Surgery. He joined MUSC in 2009 after completing a fellowship in orthopaedic oncology at Emory University where he helped establish the sarcoma program and is currently the leader of the Sarcoma Disease Focus Team at Hollings Cancer Center.

Dr. Leddy currently serves as the chairman of the Department of Orthopaedics and Physical Medicine and the chief of the Musculoskeletal Integrated Center of Clinical Excellence (ICCE). He is actively involved in both clinical and basic science research and collaborates in the Sarcoma Immunotherapy Lab.

As a member of the MUSC Department of Orthopaedics and Physical Medicine, Dr. Leddy’s primary focus is providing excellent care to patients with benign and malignant bone and soft tissues tumors in children and adults, metastatic bone cancer, fracture care, and primary and revision hip replacements.