Schedule Your Vaccine

MUSC Health offers the Pfizer vaccine and boosters.

Now vaccinating as young as 6 months old

As of June 21, 2022 MUSC Health will vaccinate children as young as 6 months old at the following locations:


  • Patients must be at least 7.5kg (16.5 lbs) to receive the vaccine at our MUSC COVID-19 vaccine locations. Please be prepared to give the clinician a recent weight of your child
  • For children under the weight of 16.5 lbs, please schedule an appointment with your pediatrician. If you do not have a pediatrician or your pediatrician is not providing the COVID -19 vaccine at this time, please call our COVID-19 scheduling line at 843-876-7227 to speak with a representative

Those with MyChart access for their children may schedule online now. If you do not have a MyChart account for your child, please call our COVID-19 help line at 843-876-7227 to schedule

COVID-19 booster shot appointments are available

  • Patients who are age 5 and older can schedule a booster shot 5 months after completion of their primary series*.
    *A primary series for non-immunocompromised patients is comprised of 2 doses, whereas a primary series for immunocompromised patients is comprised of 3 doses.
  • Immunocompromised patients who are 12 and older can schedule a second booster dose at least 4 months after completion of their first booster dose.
  • Patients who are age 50 and older can schedule a second booster dose at least 4 months after completion of their first booster dose.
  • To schedule, log in to your MyChart account (Click "Schedule an Appointment" from the top menu, then click "COVID Vaccine" from the right column) or call 843-876-7227.

En español

MyChart Vaccine Clinic Locations:

Unless otherwise indicated, all locations listed below will administer the Pfizer-BioNTech vaccine, which requires two doses.





If you do not have access to the internet or are in need of assistance scheduling your vaccine at a MyChart vaccine clinic location, please review our MyChart registration tip sheet, or call our COVID Support Line at 843-876-7227.

Vaccines by MUSC Health Division

Plans for vaccinations will be listed as they become available.

Florence Division

Visit our local MUSC Health retail pharmacy to receive your COVID-19 vaccines.

Lancaster Division

Visit our local MUSC Health retail pharmacy to receive your COVID-19 vaccines.

If you'd like a demonstration on how to schedule your vaccination appointments, this video can walk you through the process. Press the pause button on the video at any time if you need to take notes or stop on a specific point.

We also have the scheduling information in PDF form for you to download. Spanish version (PDF)

Vaccine Safety Verification

At your vaccination appointment, you will be asked to verify health information to make sure it is safe for you to receive a vaccine. Please be mindful of your answers to these statements as you schedule your appointment(s).

  • If you have already received a first dose of a COVID-19 vaccine, your second dose should be the same brand as the 1st. In exceptional situations, in which the vaccine product given for the first dose cannot be determined or is no longer available, any mRNA vaccine my be administered at a minimum or 28 days between doses. At all clinic locations, MUSC Health offers the Pfizer vaccine exclusively. It has been authorized for ages 5 and up. On rare occasions, Moderna vaccines are administered at MUSC Health community vaccine sites (special allocations by DHEC).
  • After receiving the COVID-19 monoclonal antibody infusion, you CANNOT be vaccinated within 90 days of the infusion.
  • Please reschedule if you are feeling sick on the day of your vaccination appointment.
  • If you are in isolation as a result of a positive COVID-19 test, you will not be able to be vaccinated until after your quarantine has ended.
  • If you had a severe reaction to the first dose of the COVID-19 vaccine, you should not receive the second dose.
  • If you have previously had a SEVERE reaction to any other vaccine, please plan to remain at the administration site for 30 minutes after vaccination for monitoring.


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