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Course Title Mechanisms of Diastolic Dysfunction and How to Make Them Therapeutic Targets
Presented Date 07/28/2023
Expiration Date 07/28/2026
Presenter(s) Michael Zile, M.D.
This Presenter does have relevant Financial Relationships to disclose.
   Research Grants Description of Other relationship - NHLBI, VA, DOD, CVRx, Medtronic
   Consultant - Abbott, Boston Scientific, CVRx, Corvia, Edwards, EBR, Lilly, Medtronic, Merck, Novartis, Vectorious, V Wave
This activity was not supported by an education grant or any in-kind support.

The Medical University of South Carolina designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Description This video was part of the 2023 Charleston HFpEF Conference held in July 2023.
Objectives At the end of this presentation, learners should be better able to: Gain (re-gain) an understanding of the mechanisms underlying the development of HFpEF that involve cardiomyocyte and ECM homeostasis; Develop an understanding of how these mechanisms can be targeted for the development of novel treatments for HFpEF; Identify examples of successful targeting of myosin inhibition, enhanced calcium SR re-uptake, and MRA antagonism.
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