Rena N. Grant Sickle Cell Center


What is sickle cell disease?

Sickle cell disease is the most common inherited blood disorder in the United States. Approximately 100,000 Americans and over 4,000 South Carolinians have sickle cell disease. It is a life-limiting disease that affects all parts of the body causing multi-system complications that often result in life-threatening infections, stroke, and organ damage. People living with sickle cell disease experience periodic episodes of acute pain that typically become more frequent and severe over time. This chronic, painful, life-limiting disease also takes a substantial toll on the mental health of patients and their families.

Our Mission

The mission of the MUSC Health Rena N. Grant Sickle Cell Center is to enable South Carolina citizens living with sickle cell disease to thrive physically and mentally through compassionate and innovative care, research, and education.

Outpatient & Inpatient Specialty Services

Because sickle cell disease is a complicated condition, we offer a broad range of specialty services to meet the needs of patients 18 years of age and older with the disease. The care team includes a medical director, advanced practice providers, registered nurses, a pharmacist, a social worker, and a clinical care coordinator.

Patient and family education, as well as counseling, is incorporated into all clinic visits. Our clinic provides acute care for patients with pain, fever, and other complications of sickle cell disease and comprehensive, routine care and disease-specific management.

Our patients also have access to psychiatrists, general surgeons, orthopaedists, ophthalmologists, nephrologists, cardiologists, and pulmonologists, with expertise in caring for people living with sickle cell disease. All of our specialists work closely with the Sickle Cell Center team..

Services We Offer

  • Preventive care
  • Transfusion therapy
  • Disease-modifying therapy
  • Care coordination
  • Acute pain management
  • Research treatment options
  • Specialized pharmacy services

Sickle Cell Conditions We Treat

  • Sickle cell disease
  • Sickle cell anemia
  • Sickle cell trait counseling

To schedule an appointment, please call 843-876-0888.


Rutledge Tower

135 Rutledge Avenue

Charleston, SC 29425

More Care Team Members

Yan Gros, MSN | Ambulatory Manager

Michael Howard, RN

Ife Cromwell-Milton, MSW, LMSW

Pamela Mazyck, PharmD

Rachael Newkirk | Care Coordinator